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Wednesday, September 29, 2010

Psychological or Physical Stress Effect On Cancer Treatment


Psychological or physical stress one day or two days before having chemotherapy or radiation could undermine the treatment.

Scientists suggest people about to undergo chemotherapy or radiation treatment should try to relax and avoid intense activity for 48 hours.

Experiments show that heat shock factor-1 activated another protein, known as Hsp27, that kept the tumour cells alive even after they were exposed to radiation and chemotherapy.

Hsp27, which helps to block cell death, interacts with a third protein, p21, which allows cells to repair themselves and keep dividing.

When the cells were put under stress, levels of Hsp27 reached their height within 48 hours, suggesting the protein is highly active in the two days following any stressful event that activates heat shock factor-1.

Excerpted from Health News in Brief, New Straits Times, Life & Times, p.6, September 28, 2010.

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